Petroleum extracts of Cynanchum cutum L. and structure elucidation of isolated compounds
Abstract
In present study, petroleum ether extracts of Cynanchum cutum L. isolated unknown active constituents and their structure elucidated by analytical technique. The extracts were analyzed by the GC/MS technique. The GC chromatogram showed nine peaks corresponding to four compounds. These four compounds were identified on the basis of a high percentage of matching with authentic spectrum using NIST library.
References
2. Ghosh A., Ghosh T. Herbal drugs of abuse. Syst. Rev. Pharm. 2010; 1: 141-145.
3. McClatchey W. C., Mahady G. B., Bennett B. C., Shiels L., Savo V. Ethnobotany as a pharmacological research tool and recent developments in CNS-active natural products from ethnobotanical sources. Pharmacol. Ther. 2009; 123: 239-54.
4. Patel J, Amrutiya J, Bhatt P, Javia A, Jain M, Misra A. Targeted delivery of monoclonal antibody conjugated docetaxel loaded PLGA nanoparticles into EGFR overexpressed lung tumour cells. Journal of Microencapsulation. 2018;35(2):204-17.
5. Vhora I, Patil S, Bhatt P, Misra A. Protein- and Peptide-drug conjugates: an emerging drug delivery technology. Advances in protein chemistry and structural biology. 2015;98:1-55.
6. Mangal M., Sagar P., Singh H, Raghava G. P. S., Agarwal S. M. NPACT: Naturally occurring plant-based anti-cancer compound-activity-target database. Nucleic Acids Res. 2013; 41: D1124-D1129.
7. Abdullaev F. I., Espinosa-Aguirre J. J. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detect. Prev. 2004; 28: 426-32.
8. Baker J. T., Borris R. P., Carte B., Cordell G. A, Soejarto D. D, Cragg G. M, Gupta M. P, Iwu M. M, Madulid D. R, Tyler V. E. Natural product drug discovery and development - New perspectives on international collaboration. J. Nat. Prod. 1995; 58: 1325-57.
9. Amin A, Gali-Muhtasib H, Ocker M., Schneider-Stock R. Overview of major classes of plant-derived anticancer drugs. Int. J. Biomed. Sci. (Pomona, CA, U. S.) 2009; 5:1-11.
10. Lee K. H. Current developments in the discovery and design of new drug candidates from plant natural product leads. J. Nat. Prod. 2004; 67: 273-83.
11. Cragg G. M., Newman D. J. Plants as a source of anti-cancer agents. J. Ethnopharmacol. 2005; 100: 72-9.
12. Lee K. H. Anticancer drug design based on plant-derived natural products. J. Biomed. Sci. (London, U. K.) 1999; 6:236-50.
13. Mahidol C, Ruchirawat S, Prawat H., Pisutjaroenpong S, Engprasert S, Chumsri P, Tengchaisri T., Sirisinha S., Picha P. Biodiversity and natural product drug discovery. Pure Appl. Chem. 1998; 70:2065-72.
14. Cragg G. M. Paclitaxel (Taxol): a success story with valuable lessons for natural product drug discovery and development. Med. Res. Rev. 1998; 18:315-31.
15. Bhatt P, Vhora I, Patil S, Amrutiya J, Bhattacharya C, Misra A, et al. Role of antibodies in diagnosis and treatment of ovarian cancer: Basic approach and clinical status. Journal of controlled release : official journal of the Controlled Release Society. 2016;226:148-67
The International Journal of Innovative Science & Technology affairs require a formal written transfer of copyright from the author(s) for each article published. We therefore ask you to complete and return this form, retaining a copy for your records. Your cooperation is essential and appreciated. Any delay will result in a delay in publication.
I/we have read and agree with the terms and conditions stated Page 2 of this agreement and I/we hereby confirm the transfer of all copyrights in and relating to the above-named manuscript, in all forms and media, now or hereafter known, to the International Journal of Drug Regulatory affairs, effective from the date stated below. I/we acknowledge that the IJDRA is relying on this agreement in publishing the above-named manuscript. However, this agreement will be null and void if the manuscript is not published in the IJIST.
Download link for COPYRIGHT FORM